Research of the Month March 2015

1.Clinical Research
1.1 Dyspareunia and Sexual Dysfunction after Vaginal Delivery in Thai PrimiparousWomen with Episiotomy
1.2 HLA class I supertypeassociations with clinical outcome of secondary dengue virus infections in ethnic Thais

2.Preclinical Research
2.1 Testosterone reduces AGTR1 expression to prevent β-cell and islet apoptosis from glucotoxicity

 

 

 

Presented by Office of the Deputy Dean for Research,SiMR
Building, Faculty of Medicine Siriraj Hospital, Mahidol University

Science and Technology award

Professor Dr. Kovit Pattanapanyasat, Head of Center of Excellence of Flow  cytometry, Department of Research  and  Development,  Faculty  of Medicine Siriraj  Hospital, Mahidol University  was rewarded 21st Science and Technology award for 400,000 Baht by Thailand Toray Science Foundation on 9th March 2015. Professor  Dr.  Kovit  Pattanapanyasat  is  over  25  years  expertise  in  flow cytometry  application  for  immunology,  Thalassemia  and  infectious  diseases  such as   Malaria,   Dengue   virus   and   HIV/AIDS.   Moreover,   he   developed   CD4 Lymphocyte  measurement  to  be  high  quality,  standardize  and  low  cost,  for examples,  BioLeucotag  and  Biobeads.  Inevitably,  WHO  and  Thailand  MOPH U.S. CDC   Collaboration   have   an   honorary   Professor   Dr.   Kovit   invitation   to   be   a committee  to  assess  the efficiency  of  flow  cytometry  and  he  pushed  External  Quality Assurance/EQA in Thailand for CD4 measurement.

Research of the Month January 2015

1. Multidisciplinary Research
1.1 Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer
1.2 Orientia tsutsugamushi, agent of scrub typhus, displays a single metapopulation with maintenance of ancestral haplotypes throughout continental South East Asia

2. Preclinical Research
2.1 Microparticlesin Dengue Infection Provide a Novel Biomarker to Predict Severe Clinical Outcomes

 

 

Presented by Office of the Deputy Dean for Research,SiMR
Building, Faculty of Medicine Siriraj Hospital, Mahidol University

PET Tracers Development in Oncology

On 25th November, 2014, Associate Professor Dr. Chatchawan Srisawat, Chairman of Biochemistry Department and members of Cancer Nanomedicine welcomed Professor Juri Gelovani.

Professor Juri gave 2 hours special lecture “PET Tracers Development in Oncology” for doctor and researchers at the meeting room 901, 9th Floor, SiMR building. After that he visited laboratory centers on 5th and 7th Floor and also the accomodation on 11th Floor of SiMR building.

Updates on Immunology and Endocrinology

On November 13,2014, Department of Immunology, Research Division, International Relations Division, Faculty of Medicine Siriraj Hospital, and Erasmus MC together hosted a meeting under the topic of “Updates on Immunology and Endocrinology” to Promote research collaboration and Sharing experience between both institutes at SiMR building, 12nd floor. The meeting was seasoned by several reputed speakers from Erasmus MC led by Professor Dr. Martin van Hagen, Head of Department of Clinical Immunology and Professor Dr. Aart-Jan van der Lely, Head of Department of Clinical Endocrinology, Erasmus MC.

THE AWARD OF EXCELLENCE 2014 by Faculty of Medicine Siriraj Hospita

The Award of Excellence for Clinical Research

1.Assoc. Prof. Vip  Viprakasit  Department of Pediatrics
Title : Mutations in Krüppel like factor 1 cause transfusion dependent hemolytic anemia and persistence of embryonic globin gene expression
2.Assoc. Prof. Jeerunda Santiprabhob  Department of Pediatrics
Title :Outcomes of group based treatment program with parental involvement for the management of childhood and adolescent obesity.

The  Award of Excellence for Biomedical  Research
3.Lecturer  Dr.Siwanon JirawatnotaiDepartment Pharmacology
Title:The cyclin D1 CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis.
4.Lecturer Dr.Juthathip Mongkolsapaya  Office of Research and Development
Title : A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.

The Award of Excellence for Innovative Research
5. Prof. Dr.Tararaj Dharakul  Department of Immunology
Title : Simultaneous discrimination and detection of influenza A(H1N1)pdm09 and seasonal influenza A viruses using a rapid immunogold biosensor.

Siriraj-BIOTEC researcher has successfully developed a dengue vaccine

On November 29, 2013, Dr. Boonpote Siridechadilok, researcher of Medical Biotechnology Laboratory BIOTEC who is in charge of Dengue division, department of research and development revealed in the conference press about viral development on dengue vaccine. This project was granted 100,000 USD for 18 months of research support by Grand Challenges Canada.
Dengue Hemorrhagic Fever (DHF) is a mosquito-borne tropical disease that is among the most prevalent health challenges worldwide. Although vaccine development has proven effective to certain degrees, there are 400 million DHF infected people each year, with another 3 billion people prone to this infection.
According to Dr. Boonpote, “Understanding the comprehensive details of the dengue virus and its regulation will be the most crucial essence in developing a vaccine for DHF protection.”
In the present time, most of the vaccine developers focus on the live attenuated vaccine approach screening/creation—where viral mutation will be screened in the culture, or engineered.
According to Dr. Boonpote, “The original viral engineering has less genetic diversity than developed laboratory viral engineering. The developed laboratory viral engineering broadens the genetic diversity up to 10,000 times than that of the original. Moreover, this technique can analyze with high efficiency to investigate the mutation.”
Grand Challenges Canada funding is supported by the Canadian government for projects with high impacts on health sciences, technology, social and business innovations in developing countries. This funding objective is to encourage direct practices and applications of research for the well-being of the general population. In addition, there are 3 more awarded researchers namely: Dr. Surakameth Mahasirimongkol, TB/HIV Research Foundation (THRF), Assistant Professor Dr. Thanat Chookajorn, and Dr.Yoel Lubell, Mahidol University.

The 2013 TRF-CHE-Scopus Young Researcher Award

On October 16, 2013, Lecturer Dr. Siwanon Jirawatnotai was awarded the 2013 TRF-CHE-Scopus Young Researcher Awards in Health Sciences by Professor Pavich Tongroach, Assistant Minister for Education, at The Regent Cha Am Beach Resort, Huahin, Phetchaburi.

The award was granted by the concords of Thailand Research Fund (TRF), Office of Higher Education and Elsevier publisher (journal database of Scopus). This award recognizes new and intermediate researcher, with a project(s) that is pending upon receiving the TRF funding application or a remarkable project(s) within a span of 2 years.